Elizabeth Schnorrenberg

HI! I’m a senior majoring in Chemistry. I joined the Brunold Group in January 2023. My current research involves cysteine dioxygenase (CDO) which is responsible for catabolizing excess cysteine in the body.  CDO has two isoforms, the non-crosslinked and crosslinked versions. The crosslinked CDO has a thioether crosslink between the cysteine and tyrosine substrates, and is shown to have higher catalytic efficiency than the non-crosslinked isoform. We have been using kinetic assays to determine the activity of different variants to determine what the cause of the increase of catalytic efficiency is within the crosslinked isoform.  I would love to help with any research questions you may have!